Publication Date

Spring 2023

Degree Type

Master's Project

Degree Name

Master of Science in Nursing, Family Nurse Practitioner (MSN)



First Advisor

Lisa Walker-Vischer


medication adherence, hypertension, compliance, uncontrolled hypertension, blood pressure


Chronic diseases are defined as conditions that are present for over one year and limit activities of daily living or require ongoing medical attention. Heart disease is the number one leading chronic disease in the United States, making up one third of all deaths. In turn it costs the health system $216 billion per year (Center for Disease Control and Prevention, 2023). Uncontrolled blood pressure is a key risk factor for heart disease and stroke. 1 in 2 adults will need to take prescription medication to control blood pressure and lower the risk of having a cardiovascular event. This systematic review is aimed to explore the relationship between medication adherence and blood pressure. Studies between 2012-2020 will be utilized. This systematic review did find an association between medication adherence and decreased blood pressure. Many factors played a role in medication adherence such as: health literacy, socioeconomic status, frequency of disease monitoring, co-payments and medication taking reminders. Definition of terms in Appendix A.