Title

BCl3-Activated Synthesis of COO-BODIPY Laser Dyes: General Scope and High Yields under Mild Conditions

Publication Date

4-3-2020

Document Type

Article

Department

Chemistry

Publication Title

Journal of Organic Chemistry

Volume

85

Issue

7

DOI

10.1021/acs.joc.9b03059

First Page

4594

Last Page

4601

Abstract

A general and straightforward method for the synthesis of COO-BODIPYs from F-BODIPYs and carboxylic acids is established. The method is based on the use of boron trichloride to activate the involved substitution of fluorine, which leads to high yields through rapid reactions under soft conditions. This mild method opens the way to unprecedented laser dyes with outstanding efficiencies and photostabilities, which are difficult to obtain by the current methods.

Funding Number

IT912-16

Funding Sponsor

National Institutes of Health

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