Publication Date
10-4-2022
Document Type
Article
Publication Title
Neurology
Volume
99
Issue
14
DOI
10.1212/WNL.0000000000200941
First Page
E1549
Last Page
E1559
Abstract
Background and ObjectivesThis study sought to describe migrainous headache frequency and severity and to examine the relationship between trauma, discrimination, and migraine-associated disability in a sample of sexual and/or gender minority (SGM) adults.MethodsWe performed a cross-sectional study of SGM people in The Population Research in Identity and Disparities for Equality Study from August to October 2018. The primary exposure was any trauma or discrimination, regardless of attribution. The primary outcome was moderate-severe migraine disability, as defined by a Migraine Disability Assessment (MIDAS) Questionnaire score of ≥11. We performed descriptive analysis comparing respondents with any migrainous headache with those without. Multivariable logistic regression examined the association between trauma/discrimination and migraine disability, controlling first for sociodemographic and clinical factors and then for psychiatric comorbidities.ResultsOf the 3,325 total respondents, 1,126 (33.9%) screened positive for migrainous headache by ID-Migraine criteria. Most people with migraine self-reported moderate (n = 768, 68.2%) or severe (n = 253, 22.5%) intensity. The median MIDAS score was 11 (interquartile range 5-25). Most respondents with migraine (n = 1,055, 93.7%) reported a history of trauma or discrimination. In unadjusted analysis, exposure to both trauma and discrimination was associated with higher odds of moderate-severe disability (OR 1.76, 95% CI 1.34-2.32). After adjustment for self-reported psychiatric comorbidities of anxiety, depression, and posttraumatic stress disorder, this association lost statistical significance.DiscussionMigrainous headache is common among our sample of SGM adults, and prior experiences with trauma and discrimination are associated with increased migraine disability. Our findings suggest that psychiatric comorbidities play a significant role in this relationship, identifying a potentially modifiable risk factor for disability in SGM people with migraine.
Funding Number
K23DA039800
Funding Sponsor
National Institute on Drug Abuse
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Department
Psychology
Recommended Citation
Nicole Rosendale, Elan L. Guterman, Juno Obedin-Maliver, Annesa Flentje, Matthew R. Capriotti, Micah E. Lubensky, and Mitchell R. Lunn. "Migraine, Migraine Disability, Trauma, and Discrimination in Sexual and Gender Minority Individuals" Neurology (2022): E1549-E1559. https://doi.org/10.1212/WNL.0000000000200941
