Ancient human parallel lineages within North America contributed to a coastal expansion


C. L. Scheib, University of Cambridge
Hongjie Li, University of Illinois at Urbana-Champaign
Tariq Desai, University of Cambridge
Vivian Link, Université de Fribourg
Christopher Kendall, University of Toronto
Genevieve Dewar, University of Toronto
Peter William Griffith, University of Cambridge
Alexander Mörseburg, University of Cambridge
John R. Johnson, Santa Barbara Museum of Natural History
Amiee Potter, Portland State University
Susan L. Kerr, Modesto Junior College
Phillip Endicott, Musée de l’Homme
John Lindo, Emory University
Marc Haber, Wellcome Sanger Institute
Yali Xue, Wellcome Trust Sanger Institute
Chris Tyler-Smith, Wellcome Sanger Institute
Manjinder S. Sandhu, Wellcome Sanger Institute
Joseph G. Lorenz, Central Washington University
Tori D. Randall, San Diego City College
Zuzana Faltyskova, University of Cambridge
Luca Pagani, University of Tartu
Petr Danecek, Wellcome Sanger Institute
Tamsin C. O’Connell, University of Cambridge
Patricia Martz, California State University, Los Angeles
Alan S. Boraas, Kenai Peninsula College
Brian Byrd, Far Western Anthropological Research Group Inc.
Alan Leventhal, San Jose State University
Rosemary Cambra, Muwekma Ohlone Tribe of the San Francisco Bay Area
Ronald Williamson, Archaeological Services Inc.
Louis Lesage, Huron-Wendat Nation
Brian Holguin, University of California, Los Angeles
Ernestine Ygnacio-De Soto, Santa Barbara Museum of Natural History
JohnTommy Rosas, Tongva Nation
Mait Metspalu, University of Tartu
Jay Stock, University of Cambridge
Andrea Manica, University of Cambridge
Aylwyn Scally, University of Cambridge
Daniel Wegmann, Université de Fribourg
Ripan Malhi, University of Illinois at Urbana-Champaign
Toomas Kivisild, University of Cambridge

Publication Date

June 2018

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Little is known regarding the first people to enter the Americas and their genetic legacy. Genomic analysis of the oldest human remains from the Americas showed a direct relationship between a Clovis-related ancestral population and all modern Central and South Americans as well as a deep split separating them from North Americans in Canada. We present 91 ancient human genomes from California and Southwestern Ontario and demonstrate the existence of two distinct ancestries in North America, which possibly split south of the ice sheets. A contribution from both of these ancestral populations is found in all modern Central and South Americans. The proportions of these two ancestries in ancient and modern populations are consistent with a coastal dispersal and multiple admixture events.