This article pursues a topological reading of Milestones, one of the most influential books in the history of Islamism. Written by Muslim thinker Sayyid Qutb, the general interest in this crucial text has largely remained restricted to the fields of Islamic Studies and Security Studies. This article aims to make the case for assuming a philosophical standpoint, relocating its significance beyond the above-mentioned fields. A creative and topological reading of this text will allow the spatial complexity of Qutb’s eschatological vision to be fully exposed, while also unpacking the way in which antagonistic relations have variously been articulated by this thinker. The underlying conviction is that such an examination can offer new perspectives from which to examine and develop current debates on political universalism and antagonism in the tradition of continental philosophy.