Document Type
Article
Publication Date
September 2008
Publication Title
International Journal of Data Mining and Bioinformatics
Volume
2
Issue Number
3
First Page
193
Last Page
215
Abstract
With more and more genomes being sequenced, a lot of effort is devoted to their annotation with terms from controlled vocabularies such as the GeneOntology. Manual annotation based on relevant literature is tedious, but automation of this process is difficult. One particularly challenging problem is word sense disambiguation. Terms such as |development| can refer to developmental biology or to the more general sense. Here, we present two approaches to address this problem by using term co-occurrences and document clustering. To evaluate our method we defined a corpus of 331 documents on development and developmental biology. Term co-occurrence analysis achieves an F-measure of 77%. Additionally, applying document clustering improves precision to 82%. We applied the same approach to disambiguate |nucleus|, |transport|, and |spindle|, and we achieved consistent results. Thus, our method is a viable approach towards the automation of literature-based genome annotation.
Recommended Citation
Bill Andreopoulos, Dimitra Alexopoulou, and Michael Schroeder. "Word Sense Disambiguation in Biomedical Ontologies With Term Co-occurrence Analysis and Document Clustering" International Journal of Data Mining and Bioinformatics (2008): 193-215. https://doi.org/10.1504/IJDMB.2008.020522
Comments
This article originally appeared in: Andreopoulos, B., Alexopoulou, D., and Schroeder, M. (2008). Word Sense Disambiguation in Biomedical Ontologies With Term Co-occurrence Analysis and Document Clustering. International Journal of Data Mining and Bioinformatics, 2(3), 193 - 215. Copyright © 2008 Inderscience Enterprises Ltd. The article can also be found online at this link.