Publication Date
Spring 2025
Degree Type
Doctoral Project
Degree Name
Doctor of Nursing Practice (DNP)
Department
Nursing
First Advisor
Robin Whitney
Keywords
CAR T-Cell, CAR-T, Education, Video
Abstract
This project evaluated the effectiveness of short educational videos on CAR T-cell therapy, cytokine release syndrome, neurological toxicities, and prolonged pancytopenia for blood cancer patients. At Stanford Health Care in California, in the ambulatory clinic of Blood and Marrow Transplantation and Cellular Therapy (BMT-CT), we obtained a convenience sample of individuals with multiple myeloma or lymphoma preparing for CAR T-cell therapy. A pre-and post-questionnaire assessed the patients' knowledge of CAR T-cell therapy and its side effects. Wilcoxon signed-rank tests were used to determine changes in knowledge. Thirteen patients enrolled, eight completed post-surveys, and four watched the videos. The median knowledge score did not change significantly after viewing the videos (10.09 vs. 10.32 after, z = -0.37, p = .715). Patients who watched the videos reported that they were helpful. However, most patients did not view them due to time constraints and feeling overwhelmed.
Recommended Citation
Bennett, Leslie, "Using Video Education to Improve Patient Knowledge of Cellular Therapy Side Effects: Cytokine Release Syndrome, Neurological Toxicities, & Prolonged Pancytopenia" (2025). Doctoral Projects. 188.
DOI: https://doi.org/10.31979/etd.uxe9-rxye
https://scholarworks.sjsu.edu/etd_doctoral/188
