Publication Date

Spring 2026

Degree Type

Doctoral Project

Degree Name

Doctor of Nursing Practice (DNP)

Department

Nursing

First Advisor

Robin L. Whitney

Keywords

Graft-versus-host disease (GvHD), Flowsheet, Stem cell transplant

Abstract

Graft-versus-host disease (GvHD) is a common and serious complication following allogeneic hematopoietic stem cell transplantation (HSCT). Accurate documentation of GvHD severity and management is essential for clinical decision-making, interdisciplinary communication, and regulatory reporting to organizations such as the Foundation for the Accreditation of Cellular Therapy (FACT) and the Center for International Blood and Marrow Transplant Research (CIBMTR). Despite the availability of structured documentation tools within the electronic health record (EHR), their utilization is often inconsistent. The purpose of this quality improvement project was to evaluate whether a targeted provider-focused intervention could improve completion rates of a standardized GvHD documentation flowsheet in adult outpatient allogeneic transplant encounters. A pre-post design was implemented in an outpatient transplant clinic at a comprehensive cancer center. Data were obtained from Epic SlicerDicer queries of outpatient encounters before and after the intervention. The intervention included provider education, workflow integration strategies, and a GvHD documentation tip sheet. A total of 128 outpatient encounters were analyzed, comprising 64 pre-intervention and 64 post-intervention. GvHD flowsheet utilization increased from 23.4% pre-intervention to 45.3% post-intervention. Chi-square analysis demonstrated a statistically significant association between intervention period and flowsheet use (χ²(1, N = 128) = 6.79, p = .009). Improving documentation reliability strengthens quality monitoring, regulatory compliance, and continuity of care in transplant programs.

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Other Nursing Commons

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