Characterization of a pulsatile rotary total artificial heart
Publication Date
2-1-2021
Document Type
Article
Publication Title
Artificial Organs
Volume
45
Issue
2
DOI
10.1111/aor.13810
First Page
135
Last Page
142
Abstract
This article describes the properties and performance of a rotary total artificial heart (TAH) that produces inherently pulsatile flow. The hydraulic performance of the TAH was characterized using a mock circulatory loop to simulate four physiologically relevant conditions: baseline flow, increased flow, systemic hypertension, and pulmonary hypertension. The pump has a variable shuttle rate (beats per minute), percentage dwell time, and angular velocity on either side (revolutions per minute), which allows for full control of the flow rate and pulsatility over a range of healthy and pathologic pressures and flow rates. The end-to-end length and displacement volume of the TAH are 9.8 cm and 130 mL, respectively, allowing it to fit in smaller chest cavities including those of smaller adults and juvenile humans.
Funding Number
R01 HL144113
Funding Sponsor
National Institutes of Health
Keywords
cardiovascular devices, heart failure, total artificial heart
Department
Biomedical Engineering
Recommended Citation
Patrick L. Jurney, Jeremy J. Glynn, Igor V. Dykan, Matthew W. Hagen, Sanjiv Kaul, Richard K. Wampler, Monica T. Hinds, and George D. Giraud. "Characterization of a pulsatile rotary total artificial heart" Artificial Organs (2021): 135-142. https://doi.org/10.1111/aor.13810
