Publication Date
1-17-2024
Document Type
Article
Publication Title
medRxiv
DOI
10.1101/2024.01.17.24301435
Abstract
This report presents a new method for removing electrical artifact contamination from the electrically evoked compound action potential (eCAP) evoked by single cathodic-leading, biphasic-pulse stimulation. The development of the new method is motivated by results recorded in human cochlear implant (CI) users showing that the fundamental assumption of the classic forward masking artifact rejection technique is violated in up to 45% of cases tested at high stimulation levels when using default stimulation parameters. Subsequently, the new method developed based on the discovery that a hyperbola best characterizes the artifacts created during stimulation and recording is described. The eCAP waveforms obtained using the new method are compared to those recorded using the classic forward masking technique. The results show that eCAP waveforms obtained using both methods are comparable when the fundamental assumption of the classic forward masking technique is met. In contrast, eCAP amplitudes obtained using the two methods are significantly different when the fundamental assumption of the classic forward masking technique is violated, with greater differences in the eCAP amplitude for greater assumption violations. The new method also has excellent test-retest reliability (Intraclass correlation > 0.98). Overall, the new method is a viable alternative to the classic forward masking technique for obtaining artifact-free eCAPs evoked by single-pulse stimulation in CI users.
Funding Number
1R01 DC016038, 1R01 DC017846, R21 DC019458
Funding Sponsor
National Institutes of Health
Creative Commons License
This work is licensed under a Creative Commons Attribution-No Derivative Works 4.0 License.
Department
Audiology
Recommended Citation
Jeffrey Skidmore, Yi Yuan, and Shuman He. "A new method for removing artifacts from recordings of the electrically evoked compound action potential: Single-pulse stimulation" medRxiv (2024). https://doi.org/10.1101/2024.01.17.24301435
Comments
The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.