Publication Date

1-1-2024

Document Type

Article

Publication Title

PeerJ Computer Science

Volume

10

DOI

10.7717/PEERJ-CS.2015

Abstract

One of the limitations of currently-used metabolic syndrome (MetS) risk calculations is that they often depend on sample characteristics. To address this, we introduced a novel sample-independent risk quantification method called ‘triangular areal similarity’ (TAS) that employs three-axis radar charts constructed from five MetS factors in order to assess the similarity between standard diagnostic thresholds and individual patient measurements. The method was evaluated using large datasets of Korean (n = 72, 332) and American (n = 11, 286) demographics further segmented by sex, age, and race. The risk score exhibited a strong positive correlation with the number of abnormal factors and was closely aligned with the current diagnostic paradigm. The proposed score demonstrated high diagnostic accuracy and robustness, surpassing previously reported risk scores. This method demonstrated superior performance and stability when tested on cross-national datasets. This novel sample-independent approach has the potential to enhance the precision of MetS risk prediction.

Funding Number

2021-0-01531

Funding Sponsor

Ministry of Science, ICT and Future Planning

Keywords

Chronic disease, Healthcare, Metabolic syndrome, Risk quantification, Risk score

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

Department

Applied Data Science

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