Publication Date

10-2025

Document Type

Abstract

Exhibition/Performance Dates

October 13, 2025

Publication Title

Journal of the Academy of Nutrition and Dietetics

Conference Location

Nashville, TN

Volume

125

Issue

10

DOI

10.1016/j.jand.2025.06.164

Abstract

Background

Consumption of probiotics has recently been associated with a reduced risk of cognitive decline due to its anti-inflammatory effect on the brain, via the gut-brain-axis. Current studies with probiotic supplementation indicate that probiotics may play an important role in slowing the rate of cognitive decline and protecting memory. The purpose of this study was to evaluate a potential relationship between cognitive decline and dietary intake of probiotics.

Methods

This study utilized data from NHANES, both 2011-2012 and 2013-2014 cycles. Categorical variables were analyzed using chi-square tests, and continuous variables were analyzed using General Linear Models. Participants (n = 2,689) were aged 65 or older and completed two-day 24-hour dietary recall, in addition to completion of all cognitive assessments (CERAD-WR, CERAD-DL, AFT, DSST).

Results

Probiotic intake and DSST test scores had a positive significant association (p = 0.004). DSST test scores increased across each tertile of probiotic intake (low = 35.8, med = 41.3, and hi = 44.4), out of a maximum score of 133. CERAD-WR, CERAD-DL, AFT, and global cognition were not significantly affected by dietary probiotic intake (p = 0.460, 0.950, 0.674, and 0.531, respectively).

Conclusion

These findings indicate a significant relationship between the amount of dietary probiotics consumed and increased processing speed, sustained attention, and working memory in older adults.

Comments

Poster presentation abstract at the 2025 Food & Nutrition Conference & Expo

Department

Nutrition, Food Science and Packaging

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