Abramson, Tzvia Segal
Date Updated
11-21-2024
Department
Department of Biological Sciences
Academic Rank
Professor
Educational Background
Foreign Institution, Ph.D. 1991
Stanford University, Immunology and Microbiology, Post doc. 2005
Teaching Experience
to be updated
Administrative and Professional Experience
to be updated
Service
to be updated
Selected Publications
Books
Yoav Sharoni, Tzvia Segal-Abramson and Joseph Levy. Direct effects of GnRH agonists and antagonists on mammary cancer cells.. Vol. 4 Panthenon Publishing Group UK (1992)
Joseph Levy, Tzvia Abramson, V Insler and Yoav Sharoni. Molecular mechanism of GnRH action in mammary tumors. In GnRH analogues in Cancer and Human Reproduction Vickery B H., & Lunenfeld B (Eds.) Vol. 1 Dordrecht: Kluwer Academic Publishers (1989)
Selected Articles
Dasha Zaytseva, Anusha Allawala, Joy Franco, Shea Putnam, Adam Abtahie, Nina Bubalo, Connor Criddle, Tuan Nguyen, Peter Nguyen, Shreejit Padmanabhan, Puneet Sanghera, Martina Bremer, Tzvia Abramson, and Katherine A. Wilkinson. "Lipopolysaccharide‐induced inflammation does not alter muscle spindle afferent mechanosensation or sensory integration in the spinal cord of adult mice" Physiological Reports (2018). https://doi.org/10.14814/phy2.13812
Yekyung Seong, Nicole Lazarus, Lusijah Sutherland, Aida Habtezion, Tzvia Abramson, Xiao-Song He, Harry Greenberg, and Eugene Butcher. "Trafficking receptor signatures define blood plasmablasts responding to tissue-specific immune challenge" JCI Insight (2017). https://doi.org/10.1172/jci.insight.90233
A. Smith, T. Jakoush, E. Silva and Tzvia Abramson. "Th17-like Tregs are promoted during late stages of infection with B. pertussis in mice" European Journal of Immunology Vol. 46 Iss. S1 (2016) ISSN: 1521-4141
Andrew A Smith, Tarek A Jakoush, Elvia Silva, Hana You, et al.. "Characterization of Th17-like Tregs during late stages of infection with B. pertussis in mice. Possible immunomodulation by type I interferon." The Journal of Immunology Vol. 196 Iss. 1 (2016)
Andrew A Smith, Tarek A Jakoush, Elvia Silva, Hana You, et al.. "Characterization of Th17-like Tregs during late stages of infection with B. pertussis in mice. Possible immunomodulation by type I interferon." The Journal of Immunology Vol. 196 Iss. 1 (2016)
Tzvia Abramson, Victoria Wu, Hana You, Ryan Ferguson, et al.. "The role of plasmacytoid dendritic cells in the delay of Th17 production during Bordetella pertussis infection in mice" The Journal of Immunology Vol. 192 Iss. 7 (2014)
Tzvia Abramson, Nina Bubalo, Peter Nguyen, Tuan Nguyen, et al.. "Characterization of the immune response in male and female mice following lipopolysaccharide-induced systemic inflammation" The FASEB Journal Vol. 28 Iss. 1 (2014)
Tzvia Abramson, Tuan Nguyen, Ryan Ferguson, Victoria Wu, et al.. "Pertussis toxin-dependent inhibition of trafficking receptors on plasmacytoid dendritic cells and delay in the polarization of Th17 cells expressing mucosal-associated trafficking receptors during B. pertussis infection" The Journal of Immunology Vol. 190 (2013)
Tzvia Abramson, Tuan Nguyen, Dipti Ravindra, Ryan Ferguson, et al.. "Differential and temporal immunomodulation of α4 integrin receptors on memory T cells by Bordetella pertussis and Bordetella parapertussis infection in mice" The Journal of Immunology Vol. 188 (2012) https://scholarworks.sjsu.edu/biol_pub/56/
Tzvia Abramson, Nicole J. Tarlton, Caroline M. Green, Nicole H. Lazarus, et al.. "Plasmablast frequency and trafficking receptor expression are altered in pediatric ulcerative colitis" Inflammatory Bowel Diseases Vol. 18 Iss. 12 (2012)
Tzvia Abramson, Tuan M. Nguyen, Dipti Ravindra, Brian Kwong, Sana Waheed, Ryan Ferguson, Nicole Tarlton, Victoria Wu, Christopher S. Sequeira, and Martina Bremer. "Differential Expression of Alpha 4 Integrins on Effector Memory T Helper Cells during Bordetella Infections. Delayed Responses in Bordetella pertussis" PLoS One (2012): 1-14. https://scholarworks.sjsu.edu/biol_pub/56/
Tzvia Abramson, Nicole Tarlton, Caroline Green, Jagmohan Jandu, et al.. "Multicolor flow cytometry analysis of peripheral blood lymphocytes in pediatric patients with inflammatory bowel disease" The Journal of Immunology Vol. 184 Iss. 54.7 (2011)
Tzvia Abramson, Sana Waheed, Brian Kwong, Nicole tarlton, et al.. "Modulation of trafficking receptor imprinting on T cells during Bordetella pertussis infection" The Journal of Immunology Vol. 184 (2010)
Tzvia Abramson, Hassya Kedem, and David A. Relman. "Modulation of the NF-κB Pathway by Bordetella pertussis Filamentous Hemagglutinin" PLoS ONE (2008): 1-7. https://doi.org/10.1371/journal.pone.0003825
Tzvia Abramson, Hassya Kedem and David A Relman. "Proinflammatory and Proapoptotic Activities Associated with Bordetella pertussis Filamentous Hemagglutinin" Infection and Immunity Vol. 69 Iss. 4 (2001)
Tzvia Abramson, Hava Kitrosar, Joseph Levy, A V Shally, et al.. "Direct effects of LHRH agonists and antagonists on MCF-7 mammary cancer cells." Proc. Natl. Acad. Sci. Vol. 15 Iss. 89(6) (1992)
N Sion-Vardi, J Keneti, Tzvia Segal-Abramson, Judith Giat, et al.. "GnRH specific binding sites in normal and malignant renal tissue." Journal of Urology Vol. 148 Iss. 5 (1992)
Tzvia Segal-Abramson, Judith Giat, Joseph Levy and Yoav Sharon. "Guanine nucleotide modulation of high affinity gonadotropin-releasing hormone receptors in rat mammary tumors" Molec. Cell. Endocrinol Vol. 85 (1992)
Tzvia Segal-Abramson, Joseph Levy and Yoav Sharoni. "GnRH analogs stimulate phospholipase C activity in mammary tumor membranes: modulation by GTP" Mol Cell Endocrinol. Vol. 53 Iss. 3 (1987)
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Personal Commentary
Copied from works.bepress.com
Dr. Tzvia Abramson is an Professor in the Department of Biological Sciences at San José State University. Her research interests focus on mucosal immunity, specifically on the tolerance mechanisms induced in response to infection. It is intriguing how despite common microbial recognition molecules, some microbes are able to reside within our organs, evading detection by the immune system, others trigger a strong immune response that may harm both the microbe and the host and yet others, can be tolerated by the immune system such that they thrive in our body while causing chronic disease. The organs exposed to the external environment are lined with mucosal tissue and are constantly in direct contact with microbes. The mucosa comprise a specialized network of immune and residential cells that together sustain the mucosal immunity. In my research lab, we study two aspects of mucosal immunity one triggered by a pathogen in the airway and the other autoimmune triggered inflammation in the gut: a. Immunity in respiratory tract- Bordetella pertussis - a highly contagious human respiratory pathogen that triggers a prolonged disease with fatal outcomes in infants. We are particularly interested in the strategies applied by these bacteria such that the adaptive immune response is diverted to tolerate the infection for prolonged periods of time. a. Detection of circulating immune cells with gut homing surface molecules as a tool to follow the course of inflammatory bowel diseases and to monitor the effectiveness of a variety of commonly used therapies in affected patients. Students with research interests in these fields are encouraged to contact Dr. Abramson to further discuss specific projects available.