Reduced haemodynamic coupling and exercise are associated with vascular stiffening in pulmonary arterial hypertension
Biomedical | Biomedical Engineering and Bioengineering
Inadequate right ventricular (RV) and pulmonary arterial (PA) functional responses to exercise are important yet poorly understood features of pulmonary arterial hypertension (PAH). This study combined invasive catheterisation with echocardiography to assess RV afterload, RV function and ventricular–vascular coupling in subjects with PAH.
Alessandro Bellofiore, Eric Dinges, Robert Naeije, Hamorabi Mkrdichian, Lauren Beussink-Nelson, Melissa Bailey, Michael Cuttica, Ranya Sweis, James Runo, Jon Keevil, Christopher Francois, Sanjiv Shah, and Naomi Chesler. "Reduced haemodynamic coupling and exercise are associated with vascular stiffening in pulmonary arterial hypertension" Heart (2016): 421-427. https://doi.org/10.1136/heartjnl-2016-309906
This is the Accepted Manuscript of an article that appeared in Heart, volume 103, issue 6, 2016. The Version of Record (VOR) may be found at http://dx.doi.org/10.1136/heartjnl-2016-309906